Using metagenomic sequencing to evaluate the composition of microbiome in patients with Covid-19
Metagenomic Next-Generation Sequencing (mNGS) combines the offer of detection of early stages of emerging pathogens directly from...
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Microbiology Research
At Edinburgh Genetics, our Next-Generation Sequencing (NGS) services are meticulously designed to support the diverse and dynamic field of microbiology research. Offering a deep dive into the genetic blueprint of microorganisms, our NGS capabilities enable researchers to decode microbial genomes, understand pathogen virulence, track disease outbreaks, and study complex microbial communities with unprecedented detail and accuracy.
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Whole Genome Sequencing (WGS)
Our Whole Genome Sequencing service for microorganisms provides comprehensive insights into the genetic makeup of bacteria, viruses, fungi, and other microbes. WGS is instrumental in identifying new species, understanding microbial evolution, and uncovering genetic determinants of pathogenicity and antibiotic resistance. By offering a complete view of the microbial genome, our WGS service empowers researchers to address fundamental questions in microbiology and develop targeted strategies for disease control and prevention.
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Metagenomics Sequencing
Metagenomics Sequencing offers a culture-independent approach to studying microbial communities directly from environmental, clinical, or agricultural samples. This service is pivotal for exploring microbial diversity, functional genomics, and the interactions within microbiomes. Through metagenomics, Edinburgh Genetics helps researchers decipher the roles of microbes in ecosystems, human health, and disease, paving the way for novel diagnostic tools and therapeutic approaches.
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Amplicon Sequencing
16S rRNA Sequencing for bacteria and archaea, along with ITS Sequencing for fungi, are commonly used approaches that enable the identification and classification of microorganisms within complex samples. These services are essential for microbiome studies, allowing for the analysis of microbial composition and abundance. Our standard and custom amplicon sequencing solutions provide valuable insights into microbial ecology, aiding in the study of microbial involvement in health disorders, environmental biodegradation, and agricultural productivity.
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RNA Sequencing (RNA-Seq)
RNA Sequencing explores the transcriptome of bacteria, shedding light on gene expression under various conditions, stress responses, and the regulation of virulence genes. RNA-Seq is essential for understanding bacterial adaptation to host environments, resistance mechanisms, and potential targets for novel antibiotics. Our service provides dynamic insights into bacterial physiology, contributing to the development of more effective antimicrobial strategies and therapies.
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