sRNA Sequencing
Unveil the Regulatory Power of Small RNAs
Small RNA sequencing (sRNA-Seq) offers a targeted approach to studying small non-coding RNA molecules, key players in gene regulation. Unlike total RNA-Seq, sRNA-Seq focuses on these critical regulators, including:
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MicroRNAs (miRNAs): These tiny molecules regulate gene expression by binding to messenger RNA (mRNA) and promoting its degradation or inhibiting translation.
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Small interfering RNAs (siRNAs): Similar to miRNAs, siRNAs silence gene expression but often originate from exogenous sources.
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Other small non-coding RNAs: Explore a diverse range of small RNAs with regulatory functions, like Piwi-interacting RNAs (piRNAs) and transfer RNA (tRNA) fragments.
By focusing on these potent regulators, sRNA-Seq empowers researchers to:
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Identify miRNA and siRNA signatures: Uncover unique miRNA or siRNA profiles associated with specific diseases or biological processes.
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Decipher gene regulatory networks: Elucidate how miRNAs and siRNAs fine-tune gene expression and cellular function.
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Discover novel regulatory RNAs: Explore the roles of uncharacterized small RNAs in cellular regulation.
Our team of sequencing experts leverages sRNA-Seq for various research projects, including:
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Cancer research: Identify miRNA signatures associated with tumorigenesis and metastasis.
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Neurodegenerative disease research: Explore the role of miRNAs in neurological disorders like Alzheimer's and Parkinson's disease.
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Developmental biology: Investigate the involvement of small RNAs in embryonic development and cellular differentiation.
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RNA therapeutics development: Discover novel miRNA targets for therapeutic intervention in various diseases.
