Using metagenomic sequencing to evaluate the composition of microbiome in patients with Covid-19
Metagenomic Next-Generation Sequencing (mNGS) combines the offer of detection of early stages of emerging pathogens directly from...
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Total RNA Sequencing
Unveiling the Cellular Transcript Landscape
Total RNA sequencing (RNA-Seq) is a powerful technique that provides a comprehensive analysis of a cell's RNA profile. Unlike traditional methods focusing on messenger RNA (mRNA), total RNA-Seq captures the entire spectrum of RNA molecules, including:
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Messenger RNA (mRNA): The blueprint for protein production.
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Non-coding RNA (ncRNA): Diverse RNA molecules with crucial regulatory functions. This includes long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and transfer RNAs (tRNAs).
Unlock the power of total RNA-Seq and gain a deeper understanding of gene expression with Edinburgh Genetics. Contact us today to discuss your research project and how our expertise can help you achieve your goals.
This all-encompassing approach empowers researchers to gain a holistic view of gene expression, revealing:
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Novel transcript isoforms: Explore alternative splicing events that generate protein diversity.
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Non-coding RNA expression: Uncover the regulatory roles of lncRNAs and miRNAs in cellular processes.
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Differential gene expression: Identify genes with altered expression levels under different conditions.
Total RNA-Seq Applications at Edinburgh Genetics
Our team of experts leverages total RNA-Seq to support various research endeavors, including:
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Disease biomarker discovery: Identify novel RNA signatures associated with specific diseases.
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Drug target identification: Uncover potential targets for therapeutic intervention by analyzing gene expression changes in response to drugs.
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Gene regulation studies: Decipher the complex interplay between coding and non-coding RNAs in cellular regulation.
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Functional genomics: Explore the biological functions of genes and their regulatory networks.
RNA-Seq
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