Next-generation sequencing role in pharmacogenetics and pharmacogenomics
Next-generation sequencing (NGS) represents an efficient and reliable method to evaluate the contribution of both common and rare...
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Sep 13, 2023
The link between proteogenomics and the advancement in precision medicine
The emerging discipline of proteogenomics arose from the combination of two molecular biology fields – mass spectrometry (MS)-based...
Aug 23, 2022
Chemotherapy, radiotherapy and adverse drug reaction mitigation using NGS
Chemotherapy is often aggressive and can provoke severe toxicity and adverse drug reactions (ADR). Noticeable differences also exist in...
Aug 22, 2022
Access to genetic testing and the role of effective genetic counselling
Although it is widely accepted that genetic testing is an important tool to aid early diagnosis in some patient cohorts, studies have...
Aug 22, 2022
NGS testing for CYP gene and variation in drug responses
Among the most researched pharmacogenes is the CYP gene superfamily (Fukunaga et al., 2021), which influences drug-metabolising enzymes...
Aug 22, 2022
Oncology targeted therapy with egSEQ NGS
Personalised diagnostic and precision medicine for cancer patients involves tailoring each patient’s treatment based on the genomic...
Aug 22, 2022
Recurrence monitoring of colorectal and breast cancer patients with egSEQ Comprehensive Solid Tumour
With the continuous discovery of genetic targets correlated with recurrence risk, time to recurrence (TTC) and/or overall survival, it is...
Aug 22, 2022
Clinical use of NGS in pharmacology
Among the most researched such genes are the ones belonging to the CYP gene superfamily, which is thought to cause up to 60% of...
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