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Apr 5
Using metagenomic sequencing to evaluate the composition of microbiome in patients with Covid-19
Metagenomic Next-Generation Sequencing (mNGS) combines the offer of detection of early stages of emerging pathogens directly from...
Apr 3
Exploring the HoloRuminant Microbiome
HoloRuminant is a global initiative aiming to elucidate the role of ruminant-associated microbiomes and their interplay with the host...
Mar 31
Working with the University of Gdansk in a landmark HTAD Treatment Trial
Marfan syndrome is a genetic disorder that affects the body's connective tissue, which provides strength, support, and elasticity to...
Feb 12
Insights into paleogenetics from NGS
While ‘modern’ humans are the only hominin species existing on the planet today, in the past our species has overlapped both temporally...
Jan 22
NGS in clinical histocompatibility testing
The human leukocyte antigen (HLA) region is one of the most researched parts of the human genome due to the fact multiple vital genes for...
Nov 29, 2023
Whole Exome Sequencing of Endangered Harlequin Frogs
In order to avoid extinction in a quickly changing environment, a species must adapt rapidly to avoid extinction. A group of researchers...
Nov 19, 2023
Visit from Princess Royal to the Pentlands Science Park
We were delighted and honoured to welcome Her Royal Highness The Princess Royal at the Pentlands Science Park to discuss our work in...
Aug 27, 2022
Genetic research and diagnosis of Endometriosis
Endometriosis is a gynaecological disease affecting around 10% of women of reproductive age. The main symptoms of endometriosis are pain...
Aug 27, 2022
Genome-first approach to mendelian cardiovascular disease
Since the 1990s cardiovascular genomics has been a popular area of research, heading toward a genome-first approach to the diagnosis and...
Aug 23, 2022
Chemotherapy, radiotherapy and adverse drug reaction mitigation using NGS
Chemotherapy is often aggressive and can provoke severe toxicity and adverse drug reactions (ADR). Noticeable differences also exist in...
Aug 23, 2022
The utility of low-depth Whole Genome Sequencing (WGS)
A human sample sequenced at 0.1x depth using 150 bp reads yields 2.2 million reads corresponding to measurements at 330Mbp. At 0.4x...
Aug 23, 2022
Proteogenomics, the role of NGS
The emerging discipline of proteogenomics arose from the combination of two molecular biology fields –mass spectrometry (MS)-based...
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